Dr. Christopher G Mayne
Research Interests
My research centers on immune regulation of microbe-immune interactions, and how this relationship relates to autoimmune diseases such as inflammatory bowel disease, multiple sclerosis, and systemic lupus erythematosus.
Research Details
My current research involves characterization of the role regulatory T cells play in shaping immune responses to self-antigens and microbiota antigens of the extended self. My lab is approaching this question through the development of the novel in vitro models of microbe-immune interaction. My previous research has spanned numerous areas including 1) utilization of genetic tools to develop innovative mouse models to study the role of self-antigen and microbiota-driven autoimmunity, 2) the role of vitamin D in autoimmune disease, and 3) B lymphocyte development and genetic dissection of B cell-mediated autoimmunity. In the classroom, I seek to engage and energize my students both by incorporating active learning and student-centered approaches and with an enthusiastic and passionate attitude toward learning. I also enjoy training young scientists in the lab and utilize my research as another opportunity to promote inquiry-based learning.
Education
PhD, University of Wisconsin-Madison
BS, University of Wisconsin-Platteville